Endocrine Abstracts

Acromegaly is a rare disease. In more than 99% of cases this is due to a benign pituitary growth-hormone secreting adenoma. This leads to changes in appearance, enlargement of the internal organs and, after a long period of time, to multiple comorbidities.ObjectivesTo determine which factors might have contributed to the lower quality of life in three acromegalic patients.Materials and methods<p class="ab...

Introduction: Acromegaly is an endocrine disease associated with an abnormal growth-hormone (GH) and insulin-like growth factor 1 (IGF-1) excess. Multiple studies demonstrated an association between these factors and pathways that play a major role in tumor proliferation, survival and resistance to anti-cancer therapies in many human malignancies.Objectives: We wanted to study the incidence and types of tumors which are associated with Acromegaly.<p ...

IntroductionThe use of antithyroid drugs is associated rarely with severe hepatotoxicity. Recently, due to several cases reported in the literature, acute pancreatitis was added as a severe potential adverse effect induced by methimazole. The physiopathology of methimazole induced pancreatitis is not fully understood (intrinsic toxicity or idiosyncratic drug reaction were proposed as possible mechanisms). If adverse effects occur and no other treatment o...